Covid-19 has shown us the importance of mathematical and statistical models to interpret reality, provide forecasts, and explore future scenarios. Algorithms, artificial neural networks, and machine learning help us discover the opportunities and pitfalls of a world governed by mathematics and artificial intelligence.

Simulating the behavior of a human heart, predicting tomorrow's weather, optimizing the aerodynamics of a sailboat, finding the ideal cooking time for a hamburger: to solve these problems, cardiologists, meteorologists, sportsmen, and engineers can count on math help. This book will lead you to the discovery of a magical world, made up of equations, in which a huge variety of important problems for our life can find useful answers.

This book provides a basic introduction to reduced basis (RB) methods for problems involving the repeated solution of partial differential equations (PDEs) arising from engineering and applied sciences, such as PDEs depending on several parameters and PDE-constrained optimization. The book presents a general mathematical formulation of RB methods, analyzes their fundamental theoretical properties, discusses the related algorithmic and implementation aspects, and highlights their built-in algebraic and geometric structures. More specifically, the authors discuss alternative strategies for constructing accurate RB spaces using greedy algorithms and proper orthogonal decomposition techniques, investigate their approximation properties and analyze offline-online decomposition strategies aimed at the reduction of computational complexity. Furthermore, they carry out both a priori and a posteriori error analysis. The whole mathematical presentation is made more stimulating by the use of representative examples of applicative interest in the context of both linear and nonlinear PDEs. Moreover, the inclusion of many pseudocodes allows the reader to easily implement the algorithms illustrated throughout the text. The book will be ideal for upper undergraduate students and, more generally, people interested in scientific computing. All these pseudocodes are in fact implemented in a MATLAB package that is freely available at https://github.com/redbkit

This textbook is an introduction to Scientific Computing, in which several numerical methods for the computer-based solution of certain classes of mathematical problems are illustrated. The authors show how to compute the zeros, the extrema, and the integrals of continuous functions, solve linear systems, approximate functions using polynomials and construct accurate approximations for the solution of ordinary and partial differential equations. To make the format concrete and appealing, the programming environments Matlab and Octave are adopted as faithful companions. The book contains the solutions to several problems posed in exercises and examples, often originating from important applications. At the end of each chapter, a specific section is devoted to subjects which were not addressed in the book and contains bibliographical references for a more comprehensive treatment of the material. From the review: ".... This carefully written textbook, the third English edition, contains substantial new developments on the numerical solution of differential equations. It is typeset in a two-color design and is written in a style suited for readers who have mathematics, natural sciences, computer sciences or economics as a background and who are interested in a well-organized introduction to the subject." Roberto Plato (Siegen), Zentralblatt MATH 1205.65002.

Mathematical and numerical modelling of the human cardiovascular system has attracted remarkable research interest due to its intrinsic mathematical difficulty and the increasing impact of cardiovascular diseases worldwide. This book addresses the two principal components of the cardiovascular system: arterial circulation and heart function. It systematically describes all aspects of the problem, stating the basic physical principles, analysing the associated mathematical models that comprise PDE and ODE systems, reviewing sound and efficient numerical methods for their approximation, and simulating both benchmark problems and clinically inspired problems. Mathematical modelling itself imposes tremendous challenges, due to the amazing complexity of the cardiovascular system and the need for computational methods that are stable, reliable and efficient. The final part is devoted to control and inverse problems, including parameter estimation, uncertainty quantification and the development of reduced-order models that are important when solving problems with high complexity, which would otherwise be out of reach.

This monograph addresses the state of the art of reduced order methods for modeling and computational reduction of complex parametrized systems, governed by ordinary and/or partial differential equations, with a special emphasis on real time computing techniques and applications in computational mechanics, bioengineering and computer graphics.

Several topics are covered, including: design, optimization, and control theory in real-time with applications in engineering; data assimilation, geometry registration, and parameter estimation with special attention to real-time computing in biomedical engineering and computational physics; real-time visualization of physics-based simulations in computer science; the treatment of high-dimensional problems in state space, physical space, or parameter space; the interactions between different model reduction and dimensionality reduction approaches; the development of general error estimation frameworks which take into account both model and discretization effects.

This book is primarily addressed to computational scientists interested in computational reduction techniques for large scale differential problems.

In this book we describe the magic world of mathematical models: starting from real-life problems, we formulate them in terms of equations, transform equations into algorithms and algorithms into programs to be executed on computers. A broad variety of examples and exercises illustrate that properly designed models can, e.g.: predict the way the number of dolphins in the Aeolian Sea will change as food availability and fishing activity vary; describe the blood flow in a capillary network; calculate the PageRank of websites. This book also includes a chapter with an elementary introduction to Octave, an open-source programming language widely used in the scientific community. Octave functions and scripts for dealing with the problems presented in the text can be downloaded from https://paola-gervasio.unibs.it/quarteroni-gervasio This book is addressed to any student interested in learning how to construct and apply mathematical models.

In this text, we introduce the basic concepts for the numerical modeling of partial differential equations. We consider the classical elliptic, parabolic and hyperbolic linear equations, but also the diffusion, transport, and Navier-Stokes equations, as well as equations representing conservation laws, saddle-point problems and optimal control problems. Furthermore, we provide numerous physical examples which underline such equations. We then analyze numerical solution methods based on finite elements, finite differences, finite volumes, spectral methods and domain decomposition methods, and reduced basis methods. In particular, we discuss the algorithmic and computer implementation aspects and provide a number of easy-to-use programs. The text does not require any previous advanced mathematical knowledge of partial differential equations: the absolutely essential concepts are reported in a preliminary chapter. It is therefore suitable for students of bachelor and master courses in scientific disciplines, and recommendable to those researchers in the academic and extra-academic domain who want to approach this interesting branch of applied mathematics.

The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

This monograph addresses the state of the art of reduced order methods for modeling and computational reduction of complex parametrized systems, governed by ordinary and/or partial differential equations, with a special emphasis on real time computing techniques and applications in computational mechanics, bioengineering and computer graphics. Several topics are covered, including: design, optimization, and control theory in real-time with applications in engineering; data assimilation, geometry registration, and parameter estimation with special attention to real-time computing in biomedical engineering and computational physics; real-time visualization of physics-based simulations in computer science; the treatment of high-dimensional problems in state space, physical space, or parameter space; the interactions between different model reduction and dimensionality reduction approaches; the development of general error estimation frameworks which take into account both model and discretization effects. This book is primarily addressed to computational scientists interested in computational reduction techniques for large scale differential problems.

Mathematics forms bridges between knowledge, tradition, and contemporary life. The continuous development and growth of its many branches, both classical and modern, permeates and fertilizes all aspects of applied science and technology, and so has a vital impact on our modern society. The book will focus on these aspects and will benefit from the contribution of several world-famous scientists from mathematics and related sciences, such as: Ralph Abraham, Andrew Crumey, Peter Markowich, Claudio Procesi, Clive Ruggles, Ismail Serageldin, Amin Shokrollahi, Tobias Wallisser.

Thebook comprises the contribution of several authors who are among the mostrenowned scientists working in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the pre processing of clinical data, to the set up of mathematical equations, their numerical solution, both in-vivo and in-vitro validation. They address the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are addressed. This book is addressed to all scientists (from PhD level up to professional scientists) interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system."

Following up the seminal Spectral Methods in Fluid Dynamics, Spectral Methods: Evolution to Complex Geometries and Applications to Fluid Dynamics contains an extensive survey of the essential algorithmic and theoretical aspects of spectral methods for complex geometries. These types of spectral methods were only just emerging at the time the earlier book was published. The discussion of spectral algorithms for linear and nonlinear fluid dynamics stability analyses is greatly expanded. The chapter on spectral algorithms for incompressible flow focuses on algorithms that have proven most useful in practice, has much greater coverage of algorithms for two or more non-periodic directions, and shows how to treat outflow boundaries. Material on spectral methods for compressible flow emphasizes boundary conditions for hyperbolic systems, algorithms for simulation of homogeneous turbulence, and improved methods for shock fitting. This book is a companion to Spectral Methods: Fundamentals in Single Domains.

This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamental issues are considered, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls, and the different scales coupling local and systemic dynamics. All of these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and efficient simulation techniques, and pay constant attention to applications of relevant clinical interest. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling the cardiovascular system or, more broadly, physiological flows.

This textbook is an introduction to Scientific Computing, in which several numerical methods for the computer-based solution of certain classes of mathematical problems are illustrated. The authors show how to compute the zeros, the extrema, and the integrals of continuous functions, solve linear systems, approximate functions using polynomials and construct accurate approximations for the solution of ordinary and partial differential equations. To make the format concrete and appealing, the programming environments Matlab and Octave are adopted as faithful companions. The book contains the solutions to several problems posed in exercises and examples, often originating from important applications. At the end of each chapter, a specific section is devoted to subjects which were not addressed in the book and contains bibliographical references for a more comprehensive treatment of the material.

From the review:

..".. This carefully written textbook, the third English edition, contains substantial new developments on the numerical solution of differential equations. It is typeset in a two-color design and is written in a style suited for readers who have mathematics, natural sciences, computer sciences or economics as a background and who are interested in a well-organized introduction to the subject." Roberto Plato (Siegen), Zentralblatt MATH 1205.65002.

"

This book is a collection of lecture notes for the CIME course on "Multiscale and Adaptivity: Modeling, Numerics and Applications," held in Cetraro (Italy), in July 2009. Complex systems arise in several physical, chemical, and biological processes, in which length and time scales may span several orders of magnitude. Traditionally, scientists have focused on methods that are particularly applicable in only one regime, and knowledge of the system on one scale has been transferred to another scale only indirectly. Even with modern computer power, the complexity of such systems precludes their being treated directly with traditional tools, and new mathematical and computational instruments have had to be developed to tackle such problems. The outstanding and internationally renowned lecturers, coming from different areas of Applied Mathematics, have themselves contributed in an essential way to the development of the theory and techniques that constituted the subjects of the courses.

Since the publication of "Spectral Methods in Fluid Dynamics" 1988, spectral methods have become firmly established as a mainstream tool for scientific and engineering computation. The authors of that book have incorporated into this new edition the many improvements in the algorithms and the theory of spectral methods that have been made since then. This latest book retains the tight integration between the theoretical and practical aspects of spectral methods, and the chapters are enhanced with material on the Galerkin with numerical integration version of spectral methods. The discussion of direct and iterative solution methods is also greatly expanded.

This book provides the mathematical foundations of numerical methods and demonstrates their performance on examples, exercises and real-life applications. This is done using the MATLAB software environment, which allows an easy implementation and testing of the algorithms for any specific class of problems. The book is addressed to students in Engineering, Mathematics, Physics and Computer Sciences. In the second edition of this extremely popular textbook on numerical analysis, the readability of pictures, tables and program headings has been improved. Several changes in the chapters on iterative methods and on polynomial approximation have also been

Since the publication of "Spectral Methods in Fluid Dynamics" 1988, spectral methods have become firmly established as a mainstream tool for scientific and engineering computation. The authors of that book have incorporated into this new edition the many improvements in the algorithms and the theory of spectral methods that have been made since then. This latest book retains the tight integration between the theoretical and practical aspects of spectral methods, and the chapters are enhanced with material on the Galerkin with numerical integration version of spectral methods. The discussion of direct and iterative solution methods is also greatly expanded.

Cardiovascular diseases have a major impact in Western countries. Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes, complementing the information provided to medical doctors by medical imaging and other non-invasive means, and opening the possibility of a better diagnosis and more in-depth surgical planning.This book offers a mathematically sound and up-to-date foundation to the training of researchers, and serves as a useful reference for the development of mathematical models and numerical simulation codes. It is structured into different chapters, written by recognized experts in the field, but it features a common thread with consistency of notation and expressions and systematic cross-referencing. Many fundamental issues are faced, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls; the different scales coupling local and systemic dynamics. All these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and simulation techniques. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling how the cardiovascular system works.

Mathematics forms bridges between knowledge, tradition, and contemporary life.
The continuous development and growth of its many branches, both classical and modern, permeates and fertilizes all aspects of applied science and technology, and so has a vital impact on our modern society. The book will focus on these aspects and will benefit from the contribution of several world-famous scientists from mathematics and related sciences, such as: Ralph Abraham, Andrew Crumey, Peter Markowich, Claudio Procesi, Clive Ruggles, Ismail Serageldin, Amin Shokrollahi, Tobias Wallisser

Everything is more simple than one thinks but at the same time more complex than one can understand Johann Wolfgang von Goethe To reach the point that is unknown to you, you must take the road that is unknown to you St. John of the Cross This is a book on the numerical approximation ofpartial differential equations (PDEs). Its scope is to provide a thorough illustration of numerical methods (especially those stemming from the variational formulation of PDEs), carry out their stability and convergence analysis, derive error bounds, and discuss the algorithmic aspects relative to their implementation. A sound balancing of theoretical analysis, description of algorithms and discussion of applications is our primary concern. Many kinds of problems are addressed: linear and nonlinear, steady and time-dependent, having either smooth or non-smooth solutions. Besides model equations, we consider a number of (initial-) boundary value problems of interest in several fields of applications. Part I is devoted to the description and analysis of general numerical methods for the discretization of partial differential equations. A comprehensive theory of Galerkin methods and its variants (Petrov Galerkin and generalized Galerkin), as wellas ofcollocationmethods, is devel oped for the spatial discretization. This theory is then specified to two numer ical subspace realizations of remarkable interest: the finite element method (conforming, non-conforming, mixed, hybrid) and the spectral method (Leg endre and Chebyshev expansion)."

Spectral methods, particularly in their multidomain version, have become firmly established as a mainstream tool for scientific and engineering computation. While retaining the tight integration between the theoretical and practical aspects of spectral methods that was the hallmark of their 1988 book, Canuto et al. now incorporate the many improvements in the algorithms and the theory of spectral methods that have been made since then.

This second new treatment, Evolution to Complex Geometries and Applications to Fluid Dynamics, provides an extensive overview of the essential algorithmic and theoretical aspects of spectral methods for complex geometries, in addition to detailed discussions of spectral algorithms for fluid dynamics in simple and complex geometries. Modern strategies for constructing spectral approximations in complex domains, such as spectral elements, mortar elements, and discontinuous Galerkin methods, as well as patching collocation, are introduced, analyzed, and demonstrated by means of numerous numerical examples. Representative simulations from continuum mechanics are also shown. Efficient domain decomposition preconditioners (of both Schwarz and Schur type) that are amenable to parallel implementation are surveyed. The discussion of spectral algorithms for fluid dynamics in single domains focuses on proven algorithms for the boundary-layer equations, linear and nonlinear stability analyses, incompressible Navier-Stokes problems, and both inviscid and viscous compressible flows. An overview of the modern approach to computing incompressible flows in general geometries using high-order, spectral discretizations is also provided.

The recent companion book Fundamentals in Single Domains discusses the fundamentals of the approximation of solutions to ordinary and partial differential equations on single domains by expansions in smooth, global basis functions. The essential concepts and formulas from this book are included in the current text for the reader s convenience."

This volume contains the texts of the four series of lectures presented by B.Cockburn, C.Johnson, C.W. Shu and E.Tadmor at a C.I.M.E. Summer School. It is aimed at providing a comprehensive and up-to-date presentation of numerical methods which are nowadays used to solve nonlinear partial differential equations of hyperbolic type, developing shock discontinuities. The most effective methodologies in the framework of finite elements, finite differences, finite volumes spectral methods and kinetic methods, are addressed, in particular high-order shock capturing techniques, discontinuous Galerkin methods, adaptive techniques based upon a-posteriori error analysis.

This is a book about spectral methods for partial differential equations: when to use them, how to implement them, and what can be learned from their of spectral methods has evolved rigorous theory. The computational side vigorously since the early 1970s, especially in computationally intensive of the more spectacular applications are applications in fluid dynamics. Some of the power of these discussed here, first in general terms as examples of the methods have been methods and later in great detail after the specifics covered. This book pays special attention to those algorithmic details which are essential to successful implementation of spectral methods. The focus is on algorithms for fluid dynamical problems in transition, turbulence, and aero dynamics. This book does not address specific applications in meteorology, partly because of the lack of experience of the authors in this field and partly because of the coverage provided by Haltiner and Williams (1980). The success of spectral methods in practical computations has led to an increasing interest in their theoretical aspects, especially since the mid-1970s. Although the theory does not yet cover the complete spectrum of applications, the analytical techniques which have been developed in recent years have facilitated the examination of an increasing number of problems of practical interest. In this book we present a unified theory of the mathematical analysis of spectral methods and apply it to many of the algorithms in current use."